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Senior PBPK-PD Translational Modeling Lead

Posted 2 hours 48 minutes ago by GlaxoSmithKline

Permanent
Full Time
Other
Hertfordshire, Stevenage, United Kingdom, SG1 1
Job Description

GlaxoSmithKline seeks an Associate Director to lead PBPK-PD translational modelling for oligonucleotide therapeutics and ADCs. You will translate in vitro and preclinical data into tissue exposure predictions, target engagement, and pharmacological effects in patients, with QSP and AI-enabled approaches integrated into discovery and development decisions.

You will collaborate with Discovery, Biology, Chemistry, Toxicology, Bioanalysis and Clinical Pharmacology to embed model informed drug

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