Senior Medicinal Chemist - Lead ALT Drug Discovery

The Francis Crick Institute in London is seeking a Principal Laboratory Research Scientist Medicinal Chemist to lead the medicinal chemistry for a cutting-edge ALT cancer programme. You will drive design, synthesis and optimisation of small-molecule therapies, coordinating closely with biology, pharmacology, DMPK and structural biology teams to push candidates toward selection.

You will manage external CRO activities, interpret SAR and data to guide decisions, and contribute to a dynamic,