Senior Manager, Study Oversight Manager

Career Category Clinical Job Description

If you feel like you're part of something bigger, it's because you are. At Amgen our shared mission: to serve patients - drives all that we do. It is key to our becoming one of the world's leading biotechnology companies. We are global collaborators who achieve together - researching, manufacturing and delivering ever-better products that reach over 10 million patients worldwide. It's time for a career you can be proud of. Join us.

SENIOR MANAGER STUDY OVERSIGHT LIVE

What you will do: In this vital role you will provide strategic oversight of Functional Service Provider (FSP) resources and performance at the country level, ensuring high-quality and compliant clinical trial delivery. You will drive cross-functional collaboration, supplier performance, issue resolution, and continuous improvement while developing and mentoring Study Oversight Managers. Lead oversight of FSP resources, capacity, performance, quality, and delivery from study start-up through close-out. Monitor key metrics, milestones, and quality targets, proactively addressing performance or delivery risks. Serve as an escalation point for supplier-related issues and communicate country-level trends and challenges to senior leadership. Lead governance and strengthen collaboration across FSPs, study teams, sites, and global stakeholders. Mentor and develop Study Oversight Managers, driving consistency and effective ways of working. Partner with Local Study Operations leadership to ensure appropriate staff and site oversight. Support inspection readiness, audits, regulatory inspections, and investigator site relationships. Drive continuous improvement initiatives to enhance operational efficiency, supplier engagement, and trial delivery.

WIN What we expect of you

• Degree educated with significant clinical execution experience.
• Experience leading people, teams, projects, or programs within a clinical research environment.
• Strong life sciences/biopharma clinical trial experience, within biotech, pharma, or CRO environments.
• Experience managing CROs and other clinical research vendors.
• Experience overseeing clinical operations across countries/regions with knowledge of local regulations and compliance.
• Proven management of study timelines, budgets, KPIs, enrollment, quality, and operational risks.
• Ability to lead, mentor, train, and develop cross-functional clinical teams.
• Experience supporting study start-up, site readiness, audits, inspections, and regulatory requirements.
• Understanding of EDC, data integrity, and query management.
• Strong communication, stakeholder and risk management skills across functions, suppliers, geographies, and senior leadership.
• Continuous improvement mindset with the ability to drive monitoring excellence.

THRIVE What you can expect of us

Vast opportunities to learn and move up and across our global organization

Diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act

Generous Total Rewards Plan comprising health, finance and wealth, work/life balance, and career benefits

Application due date: 31st of August 2026

Equal Opportunity Statement

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.

Please contact us to request an accommodation.

About Amgen

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology. Amgen focuses on areas of high unmet medical need and leverages its biologics manufacturing expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential. For more information, visit and follow us on