Regulatory Switching of Microtubule Motors in Cell Division

Crick Institute in London invites applications for a PhD project exploring how kinesin motors organise microtubules during cell division. The project combines biochemical reconstitution, advanced fluorescence microscopy, cryo-EM and computational analysis to reveal how motor-complexes are regulated and assembled in space and time.

The student will learn to prepare motor-microtubule assemblies, observe interactions, and interpret structural data to understand motor conformations and regulatory