Principal Data Engineer

Team: Industrial Operations & Product Supply

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Principal or Staff Data Engineer to join our IOPS IT team, building the data infrastructure and pipelines that power data-driven decision making across the organization. In this role, you will architect and optimize scalable data solutions, drive technical standards, and mentor junior engineers - while collaborating with partners across Manufacturing, Quality, and IT to deliver reliable, governed, and innovative data capabilities. This position offers the opportunity to contribute to a fast growing, science-driven organization making a meaningful difference to patients worldwide.

Discover your role

• Architect and optimize secure, scalable data pipelines (ETL/ELT) for real-time and batch processing, integrating diverse data sources and establishing CI/CD practices and fault tolerant systems
• Design data lake and warehouse solutions that ensure large datasets are organized, accessible, and of high quality; implement data modeling and schema design aligned to business needs
• Monitor pipeline performance, troubleshoot issues, and implement observability and alerting systems to maintain reliability across the data platform
• Ensure adherence to data governance policies and industry regulatory requirements including 21 CFR Part 11, GxP, and CSA; maintain comprehensive system documentation
• Leverage GenAI and MCP/orchestration platforms to enhance team efficiency and drive infrastructure innovation
• Define technical standards and design complex data engineering solutions that scale across the organization
• Mentor junior engineers, contribute to team capability growth, and serve as a technical leader across data engineering initiatives

This role requires

• BS/BA in Computer Science, Bioinformatics, or a related field
• Principal: 8+ years of relevant experience
• Staff: 10+ years of relevant experience
• Strong programming skills in Python, Java, or Scala; deep SQL expertise and relational database experience required
• Experience with NoSQL and big data technologies such as Hadoop, Spark, and Kafka; stream processing experience (Kafka, Flink) a plus
• Experience with workflow orchestration tools (Airflow, Luigi, Prefect, or similar) and containerization technologies required
• Familiarity with Biotech Enterprise Systems including MES, LIMS, and QMS preferred
• Knowledge of data security, compliance requirements, and regulatory standards including CFR Part 11 and GxP in regulated environments
• Cloud certifications a plus

We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit . For other locations, additional information will be provided during the recruitment process.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on site.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

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What people ask before they join

We take hiring seriously - because finding the right person for our mission matters as much to us as finding the right company matters to you. Our process is thorough by design: we want every new hire to feel confident they've found a place where their work truly matters, and we want to be just as confident we've found someone who'll thrive here. It's a two way conversation, not a one way interview.

Curious what that looks like step by step? Check out How We Hire.

Where You'll Make an Impact

Here, you'll collaborate with teams across regions to help move our mission forward.

We invest in your health and stability so you can focus on making meaningful impact. Below is a highlight of benefit programs that may be available to you, depending on your country of employment, role, etc.

Medical, dental and vision insurance Life insurance and disability coverage Global wellness support & benefits access Paid time off, personal/flexibility hours and holiday leave Our hiring process

From application to your first day - here's how it works.

1. EXPLORE

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See something you like? Submit your application for the role that fits your background and goals.

3. CONNECT

We review your application and if your experience is a match, we'll reach out to start the conversation. Some roles include a seminar or technical exercise - we'll always tell you in advance.

4. DECISION

After interviews and careful consideration by the hiring team, we'll follow up either way. If you're selected, we'll walk you through the offer - compensation, benefits, and start date.

5. WELCOME

Once you accept, we'll help you prepare for day one - from paperwork and office details to relocation when applicable. You'll have the support you need to start strong.

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