Postdoctoral Research Assistant

Postdoctoral Research Assistant - UOD2315

We are recruiting for an exceptional individual to join us as a postdoctoral research associate within our Group/Unit/Team to explore the role of a disease relevant kinase in B cell function in the gut. This is a fixed term appointment for 30 months, starting August 2026.

This MRC funded project will explore the role of the key kinase LRRK2, a potential drug target for Crohn's disease and Parkinson's disease, in intestinal immune homeostasis. The project involves the use of in vivo models and primary human lymphocytes to investigate the function of LRRK2 in B cells, and aims to understand the role of disease relevant LRRK2 mutations using patient samples and biochemical studies.

The successful candidate will have the chance to be involved in ground breaking research that has high translational potential, and will have opportunities to present the research at national and international meetings and to publish findings. Public engagement and patient involvement will form a key part of this position. The candidate will be trained in cutting edge proteomic technologies, human immunology, -omics analyses, spectral flow cytometry, and other state of the art techniques. Candidates with a keen interest in disease relevant human immunology, with expertise in B cells are encouraged to apply.

Strong interest in studying the biochemical underpinnings of human diseases

Focus on B cell biology

Confidence in project implementation, decision making, coordinating collaborative research

Willingness to work in a team and contribute to other projects in the lab

Writing and presenting research for publication and at conferences

Who we're looking for:

• Have a PhD in Immunology and at least one publication/preprint demonstrating research output.
• Have established skills with primary B lymphocytes and flow cytometry.
• Have a strong ability to work independently but with the communication skills and openness to work in a team.
• Be willing to foster an open and collaborative approach to science and have a strong commitment to research integrity.
• Have excellent oral and written communication skills in English.
• Have strong interpersonal skills and the ability to establish and maintain collaborations.