Metallo-β-Lactamase (MBL) Infections: Diagnosis and Management

Understand the challenges of diagnosing and managing MBL infections

Metallo-β-lactamase (MBL)-producing bacterial infections are an increasing antimicrobial resistance threat that pose challenges in diagnosis and management.

In this expert-led course, you’ll gain essential knowledge to support timely, evidence-informed decision-making, helping to improve patient care and contribute to effective antimicrobial stewardship.

The course provides an overview of diagnosis and general management principles; it does not describe treatment modalities in detail.

Explore the global burden and epidemiology of MBL infections

Investigate the international prevalence of MBL infections and the rising threat they pose to patient safety and healthcare systems.

You’ll explore key epidemiological patterns and learn how regional trends shape diagnostic and management approaches.

Examine MBL resistance mechanisms and their implications

Understand how MBL enzymes confer resistance to β-lactam antibiotics, limiting treatment options and complicating patient outcomes.

Gain insights into antimicrobial resistance and the microbiological principles underpinning MBL infections.

Identify risk factors and at-risk patient populations

Discover the patient profiles most at risk of developing MBL infections, including those in critical care and long-term hospitalisation.

Learn to conduct risk assessments and improve early detection through robust screening practices.

Identify common clinical presentations and refine diagnostic approaches

Develop the skills to differentiate MBL infections from other bacterial infections despite the overlap of clinical symptoms. You’ll explore diagnostic techniques, including phenotypic and molecular methods.

Case studies will enable you to apply your learning to real-world scenarios and consider best practices for accurate, timely detection.

This course is aimed at healthcare professionals across medical, nursing, pharmacy, and other settings involved in caring for patients with MBL infections.

This course is aimed at healthcare professionals across medical, nursing, pharmacy, and other settings involved in caring for patients with MBL infections.

• Describe the burden of disease of MBL infections internationally, nationally and locally.
• Explain the epidemiology and risk factors for MBL infections.
• Explain how MBLs confer resistance to antibiotics and the implications on treatment.
• Evaluate the laboratory methods available for the detection of MBL producers, including their strengths and limitations.
• Apply knowledge of how to manage MBL infections through case studies.